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VOLUME 6 , ISSUE 3 ( September-December, 2019 ) > List of Articles

Original Article

Poststroke Epilepsy: A Hospital-based Study

Agnibha Maiti, Soumitro Ghosh, Anup K Bhattacharya

Citation Information : Maiti A, Ghosh S, Bhattacharya AK. Poststroke Epilepsy: A Hospital-based Study. Bengal Physician Journal 2019; 6 (3):51-54.

DOI: 10.5005/jp-journals-10070-6121

License: CC BY-NC 4.0

Published Online: 03-08-2020

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction: Poststroke epilepsy (PSE) is a very important complication after cerebrovascular accident (CVA). Stroke is responsible for 10% of all seizures and about 55% of newly diagnosed epilepsy in elderly population. It may lead to longer hospitalization, worse immediate functional outcome, and high mortality. Aims and objectives: We have studied 369 CVA patients from July 2017 to June 2019 to study the prevalence of epilepsy in stroke survivors, risk factors, and clinical manifestation of PSE. Materials and methods: For this purpose, detailed clinical examination, CT scan brain, MRI brain, blood glucose estimation, serum lipid profile, and EEG were carried out. Observation: Among 369 CVA patients, 34 presented with seizure: 22 patients with early seizure (within 2 weeks) and 12 with late seizure (after 2 weeks). Most of the patients were greater than 60 years of age (27 patients). The male:female ratio was 22:12. Among 34 patients, 26 patients were of cerebral hemorrhage and 8 patients were of cerebral infarct. History of hypertension was present in 29 patients. Majority of PSE patients were diabetic (24 out of total 34). Cortical involvement was present in 29 patients, and in 5 patients there was subcortical involvement. Among 34 patients, 26 experienced focal onset seizure; 5 patients had generalized seizure; and 3 experienced status epilepticus. Conclusion: Physician should always treat stroke survivors with the risk of PSE in mind. While considerable difficulties exist in designing and conducting clinical studies of PSE, such as high heterogeneity of stroke survivors, further studies are necessary to explore primary and secondary prevention of PSE.


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