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VOLUME 6 , ISSUE 3 ( September-December, 2019 ) > List of Articles

REVIEW ARTICLE

Results of Deep Brain Stimulation for Parkinson's Disease after 30 Cases

Amit K Ghosh, Aditya Mantry, Sutirtha Hazra, Nilay Shah

Citation Information : Ghosh AK, Mantry A, Hazra S, Shah N. Results of Deep Brain Stimulation for Parkinson's Disease after 30 Cases. Bengal Physician Journal 2019; 6 (3):55-61.

DOI: 10.5005/jp-journals-10070-6123

License: CC BY-NC 4.0

Published Online: 03-08-2020

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction: Deep brain stimulation of the subthalamic nucleus (STN) is an effective therapy for medically refractory Parkinson\'s disease leading to significant improvement of Parkinsonian symptoms through functional inhibition of the STN. Aim of this study: To analyze the outcome of bilateral subthalamic nucleus, deep brain stimulation in advanced Parkinson\'s disease patients. This is a clinical observational study. Material and methods: This is the result of bilateral subthalamic nucleus-deep brain stimulation (STN-DBS) done in 30 patients for advanced Parkinson\'s disease in the Institute of Neurosciences, Kolkata, during the past 7 years (2013 to 2019, August) by the authors team. Outcome had been analyzed. Results: Excellent outcome was found after the required programming. Ninety percent patients have shown excellent result. The dosage of antiparkinsonian medications was significantly reduced, with a consequent reduction of dyskinesias. Conclusion: The effect of the STN-DBS on the motor fluctuations and on the levodopa-induced dyskinesias led to a significant improvement of motor part of Unified Parkinson Disease Rating Scale (UPDRS [III]) rating.


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  1. Groiss SJ, Wojtecki L, Südmeyer M, et al. Deep brain stimulation in Parkinson's disease. Ther Adv Neurol Disord 2009;2(6):20–28. DOI: 10.1177/1756285609339382.
  2. Lopiano L, Rizzone M, Bergamasco B, et al. Deep brain stimulation of the subthalamic nucleus: Clinical effectiveness and safety. Neurology 2001;56(4):552–554. DOI: 10.1212/WNL.56.4.552.
  3. Ghosh AK, Hazra S. Deep brain stimulation in Parkinson's disease. Tech Neurosurg Neurol 2019;2(45):TNN.000548. DOI: 10.31031/TNN.2019.02.000548.
  4. Ghosh AK. Patient selection for deep brain stimulation for Parkinson's disease: a very convenient tool. Open Access J Neurol Neurosurg 2019;10(5):555796. DOI: 10.19080/OAJNN.2019.10.555796.
  5. Rezai AR, Machado AG, Deogaonkar M, et al. Surgery for movement disorders. Neurosurgery 2008;62(Suppl 2):809–838; discussion 838-9. DOI: 10.1227/01.neu.0000316285.52865.53.
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