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VOLUME 7 , ISSUE 3 ( September-December, 2020 ) > List of Articles


A Case of Rectal Malignancy Presenting with Paraneoplastic Myopathy and Hyperpigmentation of Skin: An Interesting Case Report

Pranabananda Pal, Tathagata Ghosh, Amit K Sarkar, Chandan Chatterjee

Citation Information : Pal P, Ghosh T, Sarkar AK, Chatterjee C. A Case of Rectal Malignancy Presenting with Paraneoplastic Myopathy and Hyperpigmentation of Skin: An Interesting Case Report. Bengal Physician Journal 2020; 7 (3):60-62.

DOI: 10.5005/jp-journals-10070-7030

License: CC BY-NC 4.0

Published Online: 01-12-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Colorectal cancer manifests usually with a change in bowel habit or a bleeding per rectum. Much less commonly, colorectal cancer may present as part of paraneoplastic syndrome. Paraneoplastic syndromes may help in the timely diagnosis of the case. The authors describe a case report of a 60-year-old woman with a hyperpigmented skin rash and proximal muscle weakness who was subsequently diagnosed with rectal carcinoma in the setting of progressive muscle weakness.

  1. Silva JA, Mesquita KC, Igreja AC, et al. Paraneoplastic cutaneous manifestations: concepts and updates. An Bras Dermatol 2013;88(1):9–22. DOI: 10.1590/S0365-05962013000100001.
  2. Dourmishev LA, Draganov PV. Paraneoplastic dermatological manifestation of gastrointestinal malignancies. World J Gastroenterol 2009;15(35):4372–4379. DOI: 10.3748/wjg.15.4372.
  3. Pelosof LC, Gerber DE. Paraneoplastic syndromes: an approach to diagnosis and treatment. Mayo Clin Proc 2010;85(9):838–854. DOI: 10.4065/mcp.2010.0099.
  4. Rodríguez LP, Yurgaky JS, Otero WR, et al. A review of paraneoplastic syndromes in gastrointestinal tumors. Rev Col Gastroenterol 2017;32(3). DOI: 10.22516/25007440.155.
  5. Femia AN, Vleugels RA, Callen JP. Cutaneous dermatomyositis: an updated review of treatment options and internal associations. Am J Clin Dermatol 2013;14(4):291–313. DOI: 10.1007/s40257-013-0028-6.
  6. Martel S, De Angelis F, Lapointe E, et al. Paraneoplastic neurologic syndromes: clinical presentation and management. Curr Prob Cancer 2014;38(4):115–134. DOI: 10.1016/j.currproblcancer.2014.08.002.
  7. Shah KR, Boland CR, Patel M, et al. Cutaneous manifestations of gastrointestinal disease: part I. J Am Acad Dermatol 2013;68(2):189.e1–e21. DOI: 10.1016/j. jaad.2012.10.037.
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