Hypertriglyceridemia-induced Acute Pancreatitis: A Case Report
Ankur Poddar, Tanmay Banerjee, Tapas Bandyopadhyay, Samiul Akhtar, Sayan Kar
Citation Information :
Poddar A, Banerjee T, Bandyopadhyay T, Akhtar S, Kar S. Hypertriglyceridemia-induced Acute Pancreatitis: A Case Report. Bengal Physician Journal 2022; 9 (1):16-18.
Increased serum triglyceride level is the third most common cause of acute pancreatitis. Although a rare entity but results in severe pancreatitis with life-threatening organ dysfunction if untreated; therefore it requires a high level of clinical suspicion to be accurately diagnosed. We discuss the case of a 42-year-old man who initially presented in emergency department with suspected acute pancreatitis but who did not respond to the conservative management. On taking detailed history and clinical examination showed an evidence of hyperlipidemia. Subsequent investigations revealed acute pancreatitis secondary to hypertriglyceridemia. In this report, we tried to highlight few causes of hypertriglyceridemia, and the role of plasmapheresis and euglycemic insulin therapy in the management of hypertriglyceridemia-induced acute pancreatitis.
Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). J Am Med Assoc 2001;285(19): 2486–2497. DOI: 10.1001/jama.285.19.2486.
Fortson MR, Freedman SN, Webster PD 3rd. Clinical assessment of hyperlipidemic pancreatitis. Am J Gastroenterol 1995;90(12): 2134–2139. PMID: 8540502.
Tsuang W, Navaneethan U, Ruiz L, et al. Hypertriglyceridemic pancreatitis: presentation and management. Am J Gastroenterol 2009;104(4):984–991. DOI: 10.1038/ajg.2009.27.
Vipperla K, Somerville C, Furlan A, et al. Clinical profile and natural course in a large cohort of patients with hypertriglyceridemia and pancreatitis. J Clin Gastroenterol 2017;51(1):77–85. DOI: 10.1097/MCG.0000000000000579.
Jain D, Zimmerschied J. Heparin and insulin for hypertriglyceridemia-induced pancreatitis: case report. Sci World J 2009;9:1230–1232. DOI: 10.1100/tsw.2009.142.
Ramırez-Bueno A, Salazar-Ramırez C, Cota-Delgado F, et al. Plasmapheresis as treatment for hyperlipidemic pancreatitis. Eur J Intern Med 2014;25(2):160–163. DOI: 10.1016/j.ejim.2013.08.701.
Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med 1985;13(10):818–829. PMID: 3928249.
Preiss D, Tikkanen MJ, Welsh P, et al. Lipid-modifying therapies and risk of pancreatitis. J Am Med Assoc 2012;308(8):804. DOI: 10.1001/jama.2012.8439.
