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VOLUME 9 , ISSUE 2 ( May-August, 2022 ) > List of Articles
S Arulrhaj, Arulprakash, Aarathykannan, Chandrakumar, Manikandan, Md Faizur Rahman
Keywords : Addison's disease, Autoimmune, Hyperpigmentation
Citation Information : Arulrhaj S, Arulprakash, Aarathykannan, Chandrakumar, Manikandan, Rahman MF. A Challenging Case of Addison's Disease. Bengal Physician Journal 2022; 9 (2):48-50.
License: CC BY-NC 4.0
Published Online: 31-08-2022
Copyright Statement: Copyright © 2022; The Author(s).
Addison's disease (AD) or primary adrenocortical insufficiency results from hypofunction/dysfunction of an adrenal cortex with a decreased production of mineralocorticoids, glucocorticoids, and androgens, and with increased levels of adrenocorticotropic hormone and plasma renin activity. The AD prevalence is 110–144 cases for every million population among the developed countries.1 Autoimmune AD is the most common etiological type in adult patients, which includes about 80% of cases, followed by the second one which is post-tuberculosis AD, seen in 10–15% of the cases, the rest 5% of the cases are caused by neoplastic, vascular, or any rare genetic conditions. The most common form of AD in children is congenital adrenal hyperplasia, and it includes 72% of cases, on the other hand, autoimmune AD is responsible for 10–15% of cases.