Citation Information :
Mondal K, Dasgupta S, Mandal K, Ghosh S. Immune Thrombocytopenic Purpura Evolving into Hodgkin's Disease in a Young Boy. Bengal Physician Journal 2022; 9 (1):13-15.
Immune thrombocytopenic purpura (ITP) is a common bleeding disorder, and it may be primary (no potential etiologies found) or secondary (underlying associated conditions). The association between ITP and Hodgkin disease (HD) is well recognized in literature. ITP may occur before, during concurrent, and after the diagnosis of HD. Here we report a case of 15-year-old young boy, diagnosed as having ITP, who presented with persistent fever for a period of around 6 months and pancytopenia, and subsequently, we diagnosed HD. He responded well after chemotherapy.
Frederiksen H, Schmidt K. The incidence of idiopathic thrombocytopenic purpura in adults increases with age. Blood 1999;94(3):909–913. PMID: 10419881.
Terrell DR, Beebe LA, Vesely SK, et al. The incidence of immune thrombocytopenic purpura in children and adults: a critical review of published reports. Am J Hematol 2010;85(3):174–180. DOI: 10.1002/ajh.21616. PMID: 20131303.
Poponea N, Suede M, Muhsin Chisti M. Idiopathic thrombocytopenic purpura masking Hodgkin disease: a paraneoplastic syndrome or simply a mere association. Case Rep Oncol 2017;10(3):1116–1120. DOI: 10.1159/000485241.
Bradley SJ, Hudson GV, Linch DC. Idiopathic thrombocytopenic purpura in Hodgkin's disease: a report of eight cases. Clin Oncol (R Coll Radiol) 1993;5(6):355–357. DOI: 10.1016/s0936-6555(05)80085-8.
Landgren O, Engel EA, Pfeiffer RM, et al. Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia. J Natl Cancer Inst 2006;98(18):1321–1330. DOI: 10.1093/jnci/djj361.
Stern M, Buser AS, Lohri A, et al. Autoimmunity and malignancy in hematology–more than an association. Crit Rev Oncol Hematol 2007;63(2):100–110. DOI: 10.1016/j.critrevonc.2007.02.002.
Marino S, Di Cataldo A. A difficult diagnosis of Hodgkin lymphoma due to immune thrombocytopenic. Clin Case Rep 2015;3(3):179–182. DOI: 10.1002/ccr3.176.
