Scientific understanding of systemic lupus erythematosus (SLE) is progressing at a steady pace. Thus, there has been a paradigm shift in the understanding of the pathogenesis of SLE. As clinical experience of SLE is accumulating, the criteria for diagnosis are also being modified. Treatment of SLE still leaves a lot to be desired but every year, there are new additions and alterations. This article sums up these recent changes, especially those in the management of SLE.
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