Background: Individuals suffering from diabetes mellitus are at higher risk of all forms of sexual dysfunctions, but there is hardly any study in India that discussed all aspects of sexual activity in diabetic patients. Hence, the current study was conducted to estimate the prevalence of the sexual disorder in diabetic patients. Materials and methods: One hundred nine diabetic men were selected, who fulfilled the inclusion criteria and assessed by the International Index of Erectile Function-5 (IIEF-5) questionnaire. Result: The prevalence of erectile dysfunction (ED) was 89.9%, out of which 58.16% reported spontaneously with maximum (62.4%) having severe ED, andthe IIEF-5 score provided by patients themself and their spouses was statistically significant (p-value = 0.000). The hypoactive sexual desire and decreased libido were 25.7% and 42.2%, respectively. A total of 68.8% of participants failed to attain orgasm, 56.9% of participants had premature ejaculation but 20.2% had delayed ejaculation, and 61.47% had all three of erection, ejaculation, and orgasm problems. Conclusion: This study concluded that nine out of ten diabetic men were suffering from ED and only interviewing the male sexual partner is sufficient for the evaluation of ED and also concluded that ED is not so much social stigma nowadays. Other sexual dysfunction should be addressed for better sexual satisfaction outcomes.

Background: The coronavirus infectious disease-2019 (COVID-19) infectivity and death rates are steadily falling as we reach the declining phase of the second wave. However, there is still no surety as to when we will be finally free from the pandemic and mortality will always remain the most important factor of concern. Materials and methods: One hundred patients who died due to COVID-19 were sampled using systematic random sampling from our hospital, and demographic, clinical, blood, and radiological investigations data were collected retrospectively. An analysis of these parameters was then done using descriptive statistical methods to point out potential risk factors for mortality, which may help in formulating future hypotheses. Results: The mean age was 68.3 years, and 69% were more than 65 years of age. Sixty-one percent were males, suggesting a male preponderance. Diabetes and hypertension were the most common comorbidities. Oxygen saturation <90%, respiratory rate >24/minute, heart rate >90/minute, impaired level of consciousness, National Early Warning Score (NEWS) >12 seem to be important mortality predictors. Neutrophil/lymphocyte ratio of more than 5.2, lymphopenia, low platelet counts, low serum albumin, electrolyte disturbances, high creatinine levels, and high serum inflammatory biomarker levels all appear to contribute to mortality in COVID-19 patients. Conclusions: More studies need to be performed to test for the variety of hypotheses proposed in this study. Early identification of these mortality indicators may help us reduce mortality in such cases by timely and appropriate intervention.

Scrub typhus is a widely neglected disease, which is gaining global momentum because of its resurgence patterns. The disease is now being reported in newer regions as well aspreviously endemic areas, being called as “tsutsugamushi triangle.” Typhus is a Greek word meaning fever with stupor.

An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that started in China in the year 2019 has become a global pandemic. SARS-CoV-2 enters the host cell through the angiotensin-converting enzyme 2 (ACE2) receptor, which is known to be down-regulated in COVID-19 infected individuals. ACE inhibitors (ACEI) and angiotensin receptor blockers (ARB) can modulate and most probably up-regulate ACE2 expression and can be a therapeutic option, especially in COVID-19 patients with hypertension. ACEI itself can cause dry cough and loss of taste in some susceptible individuals, which can intimate the symptoms of COVID-19 infection itself and can put the treating physician into a diagnostic dilemma. Careful evaluation and discontinuation of the drug can reverse the symptoms dramatically.

Expanded dengue syndrome (EDS) is an atypical presentation of dengue fever with the involvement of various organ systems. We present five cases of EDS with varying features. The first and second patients had concurrent infection with falciparum malaria and vivax malaria, respectively, which made the diagnosis and treatment challenging. The third patient had coinfection with scrub typhus. The fourth patient was diagnosed with long-segment myelitis of the brain stem. The final patient in this series had a rare presentation consistent with post dengue hemophagocytic lymphohistocytosis (secondary HLH). There is no direct correlation between the severity of dengue and the type of organ involvement, and even without the classical features of dengue, serious complications can arise. In conclusion, it is of utmost importance to have a high index of suspicion and be well-informed of the different presentations and coinfections associated with EDS.